Description of ExAtlas
This is a mini version of ExAtlas, a tool for meta-analysis of gene expression data.
The mini-version is limited to mouse and human data, and does not allow registration of users. Thus, it can be used
only in the guest mode. The full version Full ExAtlas
is hosted by Elixirgen Scientific Inc.
In contrast to other software, it compares multi-component data sets and generates results for all
combinations (e.g., all gene expression profiles vs. all GO annotations). Main functions are:
(1) standard meta-analysis (fixed and random effects, z-score, Fisher's method; analysis of
(2) global correlations between gene expression data sets;
(3) gene set enrichment;
(4) gene set overlap;
(5) gene association (Expected Proportion of False Positives, EPFP);
(6) statistical analysis of gene expression (ANOVA, PCA, FDR).
Results are presented graphically as heatmaps, bar-charts, or 3-D images (PCA).
Gene expression data is extracted automatically from GEO/NCBI database. Several most popular
public data sets (e.g., GNF, Gene Ontology, KEGG, GAD phenotypes)
are pre-loaded and can be used for functional annotations.
HELP: A guide to ExAtlas.
How to cite ExAtlas: Sharov, A.A., Schlessinger, D., and Ko, M.S.H. 2015. Exatlas: An
interactive online tool for meta-analysis of gene expression data.
J. Bioinform. Comput. Biol., DOI: 10.1142/S0219720015500195.
Please report any problems to sharov (at) comcast.net